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Author

Yafeng Song

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Open access Jul 2026

A novel adeno-associated viral vector derived from human spleen isolate AAV.hu.S17

This study generated a novel recombinant AAV vector rAAV.hu.hu.S17, derived from the human spleen isolate AAV.hu.S17, and systematically evaluated its capsid features, in vitro transduction, and in vivo tissue tropism.

Wenyan Guo, Jiawen Sun, Fei Wang et al. · 0 citations
#gene editing Review Aug 2026

Mitochondrial Dysfunction as a Central Hub of Aging: From Molecular Cascades to Inter-Organ Communication Networks.

This review elucidates the core mechanisms underpinning this dysfunction, including reactive oxygen species (ROS)-induced redox imbalance, mitochondrial DNA (mtDNA) damage accumulation, impaired mitophagy, and metabolic reprogramming, and critically examines how mitochondria act as signaling hubs for inter-organ crosst...

Chao-Dong Han, Zilian Zhang, Yafeng Song · 0 citations

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