Author

Y. Tor

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Open access Sep 2026

Isothiazologuanosine (tzG) as Environmentally Sensitive Fluorescent Reporter in RNA

TzG acts as an isomorphic and isofunctional substitute for guanosine, with fluorescence properties that are sensitive to local environmental changes that enable fluorescence‐based monitoring of RNA cleavage by deoxyribozymes and of site‐specific RNA methylation by a methyltransferase ribozyme.

Julia Dietzsch, Y. Tor, Claudia Höbartner · Angewandte Chemie · 0 citations

Open access Aug 2026

Aminoglycoside antibiotics drive RNA phase separation

It is shown that aminoglycosides are a class of small-molecule RNA condensers, and neomycin B (neoB), an FDA-approved member of the family, is taken as a representative drug through which to dissect the mechanism.

Julian von Hofe, Mechi Chen, Christine Choi et al. · bioRxiv · 0 citations