Functional Improvement of dystrophic muscle by utrophin gene editing
Trinath Ghosh, S. K. Tousif Ahamed, Jun-Chao Xu et al.
· Molecular Therapy Advances · 0 citations
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AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Sep 2026
Optimization of lipid nanoparticle components and microfluidic parameters for intramuscular circRNA delivery with reduced hepatic off-targeting.
Circular RNA (circRNA) represents a promising class of RNAs for sustained protein expression and vaccine applications. However, current lipid nanoparticle (LNP) platforms remain poorly optimized for efficient intramuscular circRNA delivery, as they are primarily designed for the delivery of small interfering RNA and li...
Jie Yang, Yi-Jia Hao, Si-Ying Long et al.
· Lab on a Chip · 0 citations
Review
2026
Transient T cell therapies.
The pharmacological imperative for transient CAR expression is delineated, including lipid nanoparticles in combination with mRNA, which avoids risks of insertional mutagenesis and enables titratable, short-lived CAR expression, thereby enhancing safety management and suitability for applications beyond oncology.
Yudian Xiao, Ming-Liang Bai, M. Ang et al.
· Advances in Pharmacology · 0 citations