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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Xueping Hu

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Review Open access 2026

Innovation-driven drug discovery: Frontier exploration and breakthrough

The progress of drug discovery to the market typically requires 12 to 15 years, during which substantial financial investments are continuously made for various research and testing activities. The complexity and multifactorial nature of the disease, the complexity of the drug development process, the size of the chemi...

Shao-Qing Du, Xue-Ping Hu, E. De Clercq et al. · 0 citations
Review Jul 2026

Exploring Privileged Structure Repurposing: Target Similarity as a Catalyst for Cross-Species Drug Discovery.

Three core medicinal chemistry strategies, including side-chain replacement, conformational constraint, and scaffold hopping, are applied to optimize the lead compound and validate this strategy through representative case studies and summarize key practical challenges: off-target toxicity and difficulties in modifying...

Shaoqing Du, Kai Tang, Jinheng Li et al. · 0 citations

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