BACKGROUND
In locally advanced esophageal squamous cell carcinoma (LA-ESCC), neoadjuvant chemoimmunotherapy (NCIT) plus high-quality surgery (R0 resection with systematic lymphadenectomy >19 nodes) is a promising strategy. However, the value of adjuvant immunotherapy remains unclear. This study aimed to evaluate the as...
Jing-Wei Sun, Pei-Long Bao, Yu-Quan Bai et al.· Journal of Thoracic and Card...· 0 citations
OBJECTIVE
To compare early recurrence patterns and survival outcomes between neoadjuvant chemoimmunotherapy (NCIT) and neoadjuvant chemoradiotherapy (NCRT) in patients with locally advanced esophageal squamous cell carcinoma (ESCC).
METHODS
This retrospective cohort study included 1428 patients with stage IIB-IVA ESC...
Ci-En Sun, Chun-Ji Chen, Hua Sun et al.· European Journal of Cardio-T...· 0 citations
Esophageal Cancer: Adjuvant and Neo-Adjuvant Therapies
The optimal neoadjuvant strategy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) remains controversial. Although chemotherapy combined with PD-1 blockade has demonstrated promising activity, it is unclear whether adding rad...
Xue-Feng Leng· Diseases of the esophagus· 0 citations
The “Non-Tube No Fasting” ERAS protocol is not associated with worse clinical characteristics or outcomes of AL compared with conventional care and further attention is warranted for patient selection strategies and improved identification of delayed AL.
Yu-Hao Wen, Yi-Xuan Huang, Kang-Jun Wang et al.· Frontiers in Oncology· 0 citations
Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications
Delayed unexplained postoperative hemorrhage after esophagectomy is a rare complication. Due to its low incidence, existing reports are limited, and high-quality evidence regarding its clinical characteristics, ri...
Xue-Feng Leng, Jicheng Xiong, Yong Li· Diseases of the esophagus· 0 citations
Background Neoadjuvant chemoradiotherapy (NCRT) is standard for locally advanced esophageal squamous cell carcinoma (ESCC), while neoadjuvant immune-chemotherapy (NICT) is a promising alternative. This study compared pathological response and long-term survival between NICT and NCRT followed by surgery using a target t...
Zhi-Yu Li, Qiu-Xi Zhou, Qin Xie et al.· Frontiers in Immunology· 1 citation
The prototype-contrast boundary pixel clustering optimization effectively enhances SAM-Med3D’s capability for ESCC lesion segmentation, achieving superior performance over nnU-Net, SegVol, and MedSAM across multicenter datasets.
Si-miao Lu, Yi Zhu, Yong-Tao Han et al.· Diseases of the esophagus· 0 citations
Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications
The prognostic impact of type 2 diabetes in esophageal cancer patients receiving neoadjuvant therapy followed by surgery remains unclear. We evaluated its association with perioperative outcomes and long-term surv...
Xi-Peng Wang, Zhi-Chao Liu, Xue-Feng Leng et al.· Diseases of the esophagus· 0 citations
Esophageal Cancer: Surgical Treatment of Esophageal Cancer
Prognostic stratification remains inadequate in patients with locally advanced esophageal squamous cell carcinoma (ESCC) following neoadjuvant immunotherapy combined with chemotherapy (NICT). This multicenter study aimed to determine the prognostic...
Xue-Feng Leng, Jicheng Xiong, zigang li· Diseases of the esophagus· 0 citations
Findings challenge the unconditional interchangeability of ypN and pN in current staging systems and have direct implications for adjuvant treatment decision-making after neoadjuvant esophageal cancer therapy.
Si-miao Lu, Xue-Feng Leng· Diseases of the esophagus· 0 citations
A novel EC PCDRGs model is developed which could predict the prognosis and drug treatment sensitivity of EC patients in the future based on further validation.
Si-Han Lu, Yi Zhu, Yong-Tao Han et al.· Diseases of the esophagus· 0 citations
Findings support RAMIE as a viable alternative with comparable patient-centered outcomes, though the higher anastomotic leak rate warrants further investigation.
Si-miao Lu, Yi Zhu, Yong-Tao Han et al.· Diseases of the esophagus· 0 citations
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