Unintended omics changes in two gene-edited wheat lines exhibit less variation than in conventional lines and show no detectable adverse effects on the aphid Schizaphis graminum.
A key safety concern for gene-edited (GE) crops is whether unintended molecular changes associated with gene editing pose risks to non-target organisms (NTO). Here, we combined proteomic and metabolomic profiling with insect bioassays to assess the effects of two GE wheat lines (mildew resistance Locus O (MLO)- and Tri...