Author

Xiao-Wen Song

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Review Sep 2026

Castration-resistant prostate cancer as an adaptive tumor ecosystem: coupling tumor evolution with microenvironmental reprogramming

A system-level framework is proposed in which CRPC is viewed as an adaptive tumor ecosystem shaped by evolutionary selection, cellular plasticity, and microenvironmental co-evolution under therapeutic pressure and therapeutic strategies aimed at reprogramming or destabilizing adaptive tumor ecosystems are highlighted.

Si-Liang Wang, Xin-Yi Xu, Ming-Huang Xu et al. · Cancer Metastasis Review · 0 citations

Open access Aug 2026

Molecular and metabolic mechanisms of quercetin in liver fibrosis: an integrated network pharmacology, metabolomics, and molecular dynamics study

Introduction Liver fibrosis, a severe chronic liver injury sequela, lacks effective therapies. Quercetin, a natural flavonoid, exhibits multi-target anti-fibrotic potential. Methods This study integrated network pharmacology,metabolomics, molecular docking, and molecular dynamics simulations to investigate its mechanis...

Xiao-Wen Song, Tian-Fu Guo, Ya-Xin Li et al. · Frontiers in Pharmacology · 0 citations