Xiang-Rong Liu

SwinTransRNA: A Swin Transformer-Based Framework for Accurate Prediction of RNA Subcellular Localization

RNA subcellular localization determines the regulatory context in which microRNAs (miRNAs), circular RNAs (circRNAs), and long noncoding RNAs (lncRNAs) exert their functions, yet these RNA classes differ greatly in sequence length and circularity, making fixed-length raw-sequence representations inconvenient for cros...

PerturbBridge: Conditional Latent Schrödinger Bridge for Single-Cell Perturbation Response Prediction

scLDM: a conditional diffusion framework for single-cell perturbation prediction.

MOTIVATION Accurate prediction of single-cell responses to external stimuli is pivotal for deciphering gene regulatory mechanisms and accelerating data-driven drug discovery. However, effectively capturing the complex, non-linear mapping between intrinsic cell states and external stimuli remains an open problem. RESU...