We read with interest the recent study by Guo et al, who developed an interpretable gradient boosting machine (GBM)- based survival model for predicting secondary loss of response (SLOR) to infliximab (IFX) in patients with Crohn’s disease. 1 By integrating therapeutic drug monitoring (TDM), clinical variables, and Sur...
Ze-Ming Qiu, Xue-Yan Xia, Xian-Cheng Li· Drug Design, Development and...· 0 citations
BackgroundNon-invasive monitoring of split renal function (SRF) impairment in the context of urinary tract obstruction remains challenging. Renal scintigraphy (RS), the clinical standard, involves ionizing radiation, whereas magnetic resonance imaging (MRI)-based alternatives are underexplored.PurposeTo evaluate arteri...
Yu-Qing Cai, Lei Wang, Wen-Hao Guan et al.· Acta Radiologica· 0 citations
In vitro experiments validated the expression pattern of EEF1A1 in clear cell renal cell carcinoma and further confirmed its functional role in regulating the biological behaviors of renal cancer cells.
The central conclusion is that computational sophistication cannot repair absent chemical selectivity or non-independent validation: credible intelligent sensing requires mechanism-grounded signals, information-appropriate models, and validation at the level of the intended deployment claim.
Zhao-Jun Wu, Zhuang Sun, Kaiqiang Sun et al.· Chemical Communications· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
