Review
Aug 2026
THBS2: the key hub linking breast cancer stroma, immunity, and therapeutic response
Thrombospondin-2 has emerged as a pivotal yet paradoxical regulator within the breast cancer tumor microenvironment and is a key architect of an immunosuppressive “cold” TME, so therapeutic inhibition of THBS2 presents a promising integrative “cold-to-hot” conversion strategy.
Xi Wan, Xin-Chen Zhao, Yao Lin et al.
· Clinical and Experimental Me... · 0 citations