Xi-Pu Chen

Engineering a multifunctional bioactive coordination polymer nanoplatform for inflammation-responsive bone regeneration

Inflammatory bone diseases are closely associated with impaired osteogenic differentiation of mesenchymal stem cells (MSCs) and excessive inflammatory signaling. Sinomenine (SIN) exhibits anti-inflammatory activity; however, its therapeutic application is limited by poor bioavailability. In this work, a multifunctional...