Background Anastomotic leak (AL) is the most concerning complication after esophagectomy in the Enhanced Recovery After Surgery (ERAS) protocol. This retrospective cohort study aimed to compare the clinical characteristics and outcomes of postoperative AL in esophageal cancer patients under the ERAS protocol versus tho...
Yu-Hao Wen, Yi-Xuan Huang, Kang-Jun Wang et al.· Frontiers in Oncology· 0 citations
Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications
Delayed unexplained postoperative hemorrhage after esophagectomy is a rare complication. Due to its low incidence, existing reports are limited, and high-quality evidence regarding its clinical characteristics, ri...
Xue-Feng Leng, Jicheng Xiong, Yong Li· Diseases of the esophagus· 0 citations
Background Neoadjuvant chemoradiotherapy (NCRT) is standard for locally advanced esophageal squamous cell carcinoma (ESCC), while neoadjuvant immune-chemotherapy (NICT) is a promising alternative. This study compared pathological response and long-term survival between NICT and NCRT followed by surgery using a target t...
Zhi-Yu Li, Qiu-Xi Zhou, Qin Xie et al.· Frontiers in Immunology· 0 citations
Esophageal Cancer: Other
Precise segmentation of esophageal squamous cell carcinoma (ESCC) lesions on CT imaging is essential for treatment planning. While the Segment Anything Model for 3D medical images (SAM-Med3D) shows promise, its performance in delineating tumor boundaries remains suboptimal. We prop...
Si-miao Lu, Yi Zhu, Yong-Tao Han et al.· Diseases of the esophagus· 0 citations
Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications
The prognostic impact of type 2 diabetes in esophageal cancer patients receiving neoadjuvant therapy followed by surgery remains unclear. We evaluated its association with perioperative outcomes and long-term surv...
Xi-Peng Wang, Zhi-Chao Liu, Xue-Feng Leng et al.· Diseases of the esophagus· 0 citations
Esophageal Cancer: Surgical Treatment of Esophageal Cancer
Prognostic stratification remains inadequate in patients with locally advanced esophageal squamous cell carcinoma (ESCC) following neoadjuvant immunotherapy combined with chemotherapy (NICT). This multicenter study aimed to determine the prognostic...
Xue-Feng Leng, Jicheng Xiong, zigang li· Diseases of the esophagus· 0 citations
Findings challenge the unconditional interchangeability of ypN and pN in current staging systems and have direct implications for adjuvant treatment decision-making after neoadjuvant esophageal cancer therapy.
Si-miao Lu, Xue-Feng Leng· Diseases of the esophagus· 0 citations
A novel EC PCDRGs model is developed which could predict the prognosis and drug treatment sensitivity of EC patients in the future based on further validation.
Si-Han Lu, Yi Zhu, Yong-Tao Han et al.· Diseases of the esophagus· 0 citations
Findings support RAMIE as a viable alternative with comparable patient-centered outcomes, though the higher anastomotic leak rate warrants further investigation.
Si-miao Lu, Yi Zhu, Yong-Tao Han et al.· Diseases of the esophagus· 0 citations
A retrospective analysis of a prospectively maintained international multicenter database comprising 2,490 patients who underwent curative-intent esophagectomy across four centers found three-field lymphadenectomy uniquely confers high recurrent laryngeal nerve palsy and chylothorax rates despite low mortality.
Si-miao Lu, Yi Zhu, Yong-Tao Han et al.· Diseases of the esophagus· 0 citations
In this international multicenter analysis of 2,449 ESCC patients, neoadjuvant therapy was not associated with improved survival after esophagectomy and remained an independent predictor of worse OS and DFS across univariate, multivariable, PSM, and IPTW analyses.
Si-miao Lu, Yi Zhu, Qiulin Shi et al.· Diseases of the esophagus· 0 citations
Symptom persistence does not adversely affect overall survival; its association with improved DFS likely reflects the tumor-control benefit of adjuvant therapy.
Si-miao Lu, Yi Zhu, Yong-Tao Han et al.· Diseases of the esophagus· 0 citations
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