Wen-Long Xing

Sequence–activity mapping and model-guided engineering of the phenol-responsive DmpR–Po σ54 promoter

Promoters are core cis-regulatory elements that determine gene expression levels and dynamic responses, and their quantitative engineering directly dictates the performance of synthetic biological systems such as whole-cell biosensors. However, the transcriptional output of complex inducible systems, exemplified by σ...