Brain metastases are common in epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) and remain clinically challenging despite the improved central nervous system activity of third-generation EGFR tyrosine kinase inhibitors (EGFR-TKIs). Because direct comparisons between active first-line c...
Background Antibody-drug conjugates (ADCs) are being evaluated in advanced small cell lung cancer (SCLC), but the available trials include different targets, constructs, doses, and treatment settings. We aimed to determine the overall range of reported activity and safety while clarifying whether the evidence supports...
Pei-Pei Zhang, Wei-Xin Zhao, Jia-Yu Ma et al.· Translational Cancer Researc...· 0 citations
Experimental validation confirms BSG's protein expression and prognostic relevance in LUAD and indicates that high BSG expression is an independent prognostic factor for poor survival in LUAD.