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Open access Sep 2026

The deubiquitinating enzyme UCHL3 promotes bladder cancer progression and glycolysis through enhancing PKM2 protein stability

It is demonstrated that UCHL3 plays a pivotal role in stabilizing PKM2, which in turn facilitates glycolysis and tumorigenesis in BCa, suggesting that UCHL3 may prove to be a potential target for the treatment of BCa.

Geng-Sheng Shi, Yan-Yan Wu, Ying-Ying Wang et al. · 0 citations
Review Open access Sep 2026

Urine-derived induced pluripotent stem cells for non-invasive diagnosis of bladder cancer

The biological rationale, reprogramming methodology, and diagnostic potential of urine-derived iPSCs (UDiPSCs) in the context of BLCA detection and monitoring are reviewed and a tiered strategy in which methylation is assessed in parental urinary cells, genomic variants in reprogrammed clones, and transcriptional pheno...

Yuan Zhu, J. Shang, Xin Zhang et al. · 0 citations

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