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Author

W. Walter

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Open access Sep 2026

Unbiased, systematic surfaceome profiling of Acute Leukemia to identify novel immunotherapy targets

An unbiased atlas of the whole cell and surface proteomes of 25 commonly used leukemic cell lines, encompassing both lymphoid and myeloid lineages, and a variety of driver mutations, is presented, creating a resource for understanding these widely used models.

Benson M. George, Anna Rodríguez-Pöhnlein, D. DeCastro et al. · 0 citations
Open access Sep 2026

Csnk1a1 E98 mutations rewire signaling and metabolism in del(5q) myelodysplastic neoplasms.

Deletion of chromosome 5q [del(5q)] is the most common cytogenetic abnormality in myelodysplastic neoplasms (MDS) and results in haploinsufficiency of multiple genes, including CSNK1A1. Recurrent CSNK1A1 mutations, predominantly affecting the E98 hotspot, occur almost exclusively in del(5q) MDS and are associated with...

Stephani Schmitz, Juliette E. Pearce, S. Martinez-Høyer et al. · 1 citation

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