The immune system protects the body against harmful agents and is composed of several molecules that perform this function. However, when this system attacks the body’s own cells, autoimmunity is established, as it becomes unable to distinguish self from non-self, which characterizes autoimmune diseases. Systemic lupus...
Daniel Lemes da Costa, Nina Hummel Deliberali, Vitória Cardoso Ribeiro da Silva et al.· Research, Society and Develo...· 0 citations
Introduction: Hodgkin lymphoma (HL) is a hematological malignancy characterized by Hodgkin and Reed-Sternberg cells embedded in a tumor microenvironment rich in inflammatory mediators and immune cells, which plays a central role in disease progression and immune evasion. Among these components, myeloid-derived suppress...
B. Fischer, Maria Eduarda Anacleta Borborema Santos, Vitória Gabriela Porfirio Lemes et al.· Revista Brasileira de Cancer...· 0 citations
Background: Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Immune evasion and chronic inflammation are central determinants of tumor progression and therapeutic resistance. We aimed to analyze recent scientific literature addressing the role of myeloid-derived suppressor cells (MDS...
Jeiciane Gleicilene Silva, Ruan de Moura Fabricio de Siqueira, Rone Cardoso Magalhães et al.· Research, Society and Develo...· 0 citations
Sepsis is characterized by a dysregulated inflammatory response that frequently progresses to profound immunosuppression. In this context, myeloid-derived suppressor cells (MDSCs) play a central role in immune regulation by limiting tissue damage while simultaneously contributing to immune paralysis. This study aimed t...
A. Teixeira, Maria Vitória Stoffel Damasceno Boquimpani, Desyreé de Farias Gonçalves et al.· Research, Society and Develo...· 0 citations
Findings reinforce the central role of MDSCs in colorectal cancer progression and highlight their potential as therapeutic targets, but the high heterogeneity of these cells and the lack of standardized methods for their identification remain challenges for their clinical application.
Maria Fernanda Imperio Pereira, Emilly Paschoal de Oliveira, Valéria de Lima Kaminski· Research, Society and Develo...· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
