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Author

V. Solovyeva

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#gene editing Review Open access Aug 2026

Genetically Modified MSCs for Targeted Regeneration: Balancing Efficacy, Biosafety, and GMP Standardization

Development of safe-harbor integration and B2M/CIITA-based hypoimmunogenic designs as strategies to reduce engineering-related batch variability and HLA-dependent donor variability support a transition from empirical optimized MSC preparations toward molecularly defined cellular medicines with predefined genotype, expression, potency, and safety attributes.

Kristina V. Kitaeva, I. Filin, A. Rizvanov et al. · 0 citations
Review Open access Aug 2026

Application of Mesenchymal Stromal Cells and Their Exosomes in Neurodegenerative Diseases and Lysosomal Storage Diseases

This review provides a roadmap for translational decision-making and identifies critical gaps that must be addressed before MSC-based therapies can be integrated into routine neurological practice.

A. I. Ayupova, Angelina S. Sidorova, Ekaterina A. Luzina et al. · 0 citations

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