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#gene editing Aug 2026

A 3D In Vitro Co-Culture Model to Investigate Tumor-Endothelial Interactions in NF2-Associated Meningiomas

A 3D-tumoroid model is established and Apelin (APLN), the ligand for APLNR, is identified as a basally upregulated angiogenic factor in NF2-deficient meningiomas, suggesting that APLN expression is regulated, at least in part, by mTORC1.

Srirupa Bhattacharyya, R. Beauchamp, V. Ramesh · 0 citations