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Author

Tsu-Ming Chien

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Jul 2026

Aurone analog LYK01 exerts oxidative stress-dependent antiproliferation, G2/M arrest, apoptosis, and DNA damage of oral cancer cells involving MAPK modulation

In conclusion, LYK01 exhibits preferential antiproliferative effects in oral cancer cells —mediated by oxidative stress and MAPK-associated pathways—while exhibiting limited cytotoxicity toward normal cells.

Yan-Ning Chen, Chia-Hung Yen, C. Yen et al. · 1 citation

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