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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Tianyi Fang

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Sep 2026

MCAT-mediated mitochondrial fatty acid metabolism regulates Lauren subtype divergence and suppresses gastric cancer progression through ROS/P53-dependent mitophagy and ferroptosis.

Findings establish Malonyl-CoA:ACP transacylase (MCAT), a Lauren subtype-associated gene encoding a key mitochondrial fatty acid synthesis (mtFAS) enzyme, as a metabolic switch that links ROS/P53-dependent cell death and therapeutic target for GC.

Yu-Fei Wang, Meng Zhu, Xin Yin et al. · 0 citations

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