Background/Objectives: Claudin 18.2 (CLDN18.2) has emerged as a clinically actionable therapeutic target in gastrointestinal malignancies; however, its expression profile and prognostic significance in cholangiocarcinoma (CCA) remain incompletely characterized. This study investigated CLDN18.2 expression in CCA and eva...
T. Toyran, Kivilcim Eren Ates, F. Pi̇şki̇n et al.· Journal of Clinical Medicine· 0 citations
Purpose: Enhancer of zeste homolog 2 (EZH2) is an epigenetic regulator implicated in the pathogenesis of diffuse large B-cell lymphoma, but the prognostic value of its protein expression is uncertain. We evaluated EZH2 expression and its associations with clinicopathological features and survival.Materials and Methods:...
Mehmet Mutlu Kıdı, Mehmet Turker, Sedat Biter et al.· Cukurova Medical Journal· 0 citations
Background/Objectives: The prognosis of metastatic rectal cancer remains poor, and few reliable prognostic biomarkers are available. DHX9 and CD47 have been implicated in colorectal cancer biology, but their prognostic value in metastatic disease remains unclear. We evaluated the associations of DHX9 and CD47 expressio...
Ş. Yaslıkaya, Ş. A. İpek, T. Toyran et al.· Medical Science· 0 citations
AbstractAim: Gastrointestinal stromal tumors (GISTs) exhibit marked heterogeneous clinical behavior that is not fully captured by conventional risk classification systems. This study aimed to evaluate the prognostic significance of loss of p16 expression and EZH2 overexpression and their relationship with clinicopathol...
T. Toyran, K. Ates, T. Köşeci et al.· Cukurova Anestezi ve Cerrahi...· 0 citations
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