Spatiotemporal Control of Genetic and Epigenetic Editing through Covalent Tethering of CRISPR Nanoparticles to Zwitterionic Microgels
A defined biorthogonal conjugation system that tethers non-viral nanoparticles to biomaterial platforms for sustained and localized CRISPR gene editing is established.
Josh P. Graham, Erika E. Wheeler, J. K. Leach et al.
· bioRxiv · 0 citations