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T. Ahearn

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Open access Sep 2026

Genetic and cellular architecture of breast cancer risk across ancestries.

Results indicate substantial cross-ancestry sharing of breast cancer polygenic architecture, highlight a consistent contribution of regulatory variation, and identify convergent cellular contexts that motivate functional follow-up and inform expectations for the transferability and attainable performance of common-vari...

James L. Li, Maria Zanti, Jacob Williams et al. · 0 citations
Open access Aug 2026

Performance of general-population breast cancer risk prediction models in an international consortium

Existing BC risk prediction models provided similar risk discrimination across multiple cohorts, although there was overestimation of risk for high-risk individuals, which supports development of a unified risk model for diverse populations that leverages appropriate incidence rates.

K. Brantley, T. Ahearn, E. Norton et al. · 0 citations

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