Microbiome Research in Rare Multiple System Atrophy: Alpha-Synuclein Seeding via Gut-Brain Axis
Although recent studies suggest the dysbiosis of gut microbiome in multiple system atrophy (MSA), particularly a decrease in Akkermansia muciniphila, as a contributor to dysfunctional intestinal barrier and alpha-synuclein spreading to the brain, new methods, including fecal RT-QuIC, smell testing, microbiota replac...