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Author

Song-Ming Zhang

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#machine learning Preprint Aug 2026

PertMind: Eliciting Emergent Biological Reasoning in LLM via Reinforcement Learning on Cellular Perturbation Data

It is shown that cellular perturbation atlases can instead become reinforcement-learning environments, where measured gene responses provide computable rewards for biological reasoning, and introduces PertMind, which combines trusted-trajectory supervised initialization with gene-, pathway-, and format-level reinforcem...

Zhen-Chao Tang, Xiao-Gang Xu, Jia-Fei Wu et al. · 0 citations
#artificial intelligence Open access Mar 2026

SCALE: Scalable Conditional Atlas-Level Endpoint Transport for virtual cell perturbation prediction

A conditional transport model that represents cells as unordered sets and predicts treated populations without cell-level matching that enables perturbation-specific prediction from unpaired populations and supports experimental prioritization is presented.

Shui-Zhou Chen, Lang Yu, Xu Lin et al. · 0 citations

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