Simon Scheuring

High-Speed AFM of Membrane Proteins: From Dynamic Imaging to Integrative Structural Biology

High-speed atomic force microscopy (HS-AFM) enables direct, label-free visualization of membrane proteins in lipid bilayers with nanometer spatial resolution and millisecond temporal resolution. Recent studies revealed transient conformational states, dynamic oligomerization changes, and membrane-mediated organization...

Self-supervised image denoising and restoration method for atomic force microscopy

Scanning probe microscopy (SPM) distinguishes itself from light and electron microscopy by sensing surface interactions with a nanoscale probe, rather than relying on the detection of particles or waves; and has evolved into a versatile tool across several fundamental and applied research fields. SPM uses raster-scanni...

HS-AFM Applications to Study Membrane Proteins.