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Si-Jin Chen

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Open access Sep 2026

Large-scale structural analysis of pre-mRNA structure using RADIS

This work has developed RADIS (Reactivity Analysis of Deep and Intergenic RNA Structure), a strategy that yields strand-resolved chemical probing reactivity profiles across entire intron-rich loci by creating tiled arrays of RNAs that comprehensively span long genomic distances.

Claire Fleurisson, Si-Jin Chen, Ryan M. Macdonald et al. · 0 citations

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