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Shinya Yamada

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#gene editing Open access Sep 2026

DNAH14 knockout mice as a model of chronic hydrocephalus: cilia and brain-related pathology

Idiopathic normal pressure hydrocephalus (iNPH) is characterized by gait disturbance, cognitive impairment, and urinary incontinence. Emerging evidence suggests that ependymal ciliary dysfunction contributes to the pathophysiology of chronic hydrocephalus, including iNPH. We previously identified DNAH14 as a causative...

Kaito Kawamura, Madoka Nakajima, Masakazu Miyajima et al. · 0 citations

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