M-SCAN: Multi-Scale Constrained Analysis of Metabolic Networks for Genome-Scale Flux Inference in Pan-Cancer Cohorts
# M-SCAN RNA-to-pFBA Tutorial M-SCAN builds Human-GEM reaction-capacity constraints from RNA expression, optional deleterious mutation attenuation, predicted kcat values, and medium constraints, then runs pFBA. The bundled three-sample CCLE example reproduces the Figure 2 mini-reference outputs and is also a template f...
Songwon Lim, Jae Woo Baek, Y David Seo et al.
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