Author

Shikhi Baruri

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Review Open access Aug 2026

Integrative Epigenomics: Bioinformatics Strategies for Multi-Omics Data Analysis in Health and Disease

Background: Epigenomics has emerged as an essential field in modern molecular biology, providing a critical layer of gene regulation. DNA methylation, histone modifications and alterations to the chromatin accessibility of DNA have been widely associated with complex diseases including cancer. The most recent developme...

Shikhi Baruri, Lalit Batra, Sohome Adhikari et al. · Epigenomes · 0 citations

#gene editing Open access Aug 2026

Comparative Analysis of Lifecycle-Dependent A to I RNA Editing in Three Members of the Microbotryum violaceum Fungal Complex

Gene expression analysis revealed that certain genes, uniquely edited during the mating stage of MvSup, tend to be upregulated in the haploid stage but downregulated during mating, and vice versa, while the a2 haploid strain of MI had fewer editing sites compared to other haploid strains.

Shikhi Baruri, Nasara Shamsudeen, Alycia C. R. Lackey et al. · Journal of Fungi · 0 citations

Review Open access Jul 2026

SNP Detection Strategies in Genomic Research: A Comparative Review of Major Tools, Algorithms, Challenges and Applications

This review compares SNP detection programs such as GATK, BCFtools, FreeBayes, SAMtools, SAMtools, and DeepVariant and their algorithmic structures, namely pileup- based, haplotype-based, and machine-learning approaches and suggests that no single tool is the best.

Shikhi Baruri, S. Khanal · Nepal Journal of Biotechnolo... · 0 citations