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Sandra Diederich

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Open access Aug 2026

Viral dissemination and diagnostic insights from experimental infection of sheep with Crimean-Congo hemorrhagic fever virus

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne orthonairovirus widely distributed across Asia, Africa, the Middle East, and Southern Europe, causing severe illness and hemorrhagic fever in humans. While sheep usually show no clinical symptoms, they develop viremia and can play a key role in transmitting...

B. Gutjahr, L. M. Michaely, Caroline Bost et al. · 0 citations
#gene editing Open access Aug 2026

Noncanonical P gene mRNA editing in Cedar virus generates a U protein that is required for efficient virion production

It is shown that Cedar virus does use mRNA editing, but at an unusual sequence and by inserting either an adenine or a guanine nucleotide and generating a previously unknown protein, termed U, that shares selected features with the V and W proteins of other henipaviruses.

H. Schwotzer, Patricia Schupp, Richard Küchler et al. · 0 citations

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