Author

S. Yamada

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Open access Aug 2026

HIF-1α integrates metabolic and immunoregulatory programs in RORγt⁺ regulatory T cells during intestinal inflammation

HIF-1α is identified as a context-dependent checkpoint that connects hypoxia-responsive transcription to mitochondrial fitness and inflammatory plasticity in intestinal RORγt⁺ Treg.

Marcella Cipelli, E. M. da Silva, Luísa Menezes-Silva et al. · bioRxiv · 0 citations

Review Open access Jul 2026

Kidney Health in a Changing Climate: Emerging Disease Patterns and Driving Mechanisms.

It is argued that a comprehensive understanding of these multilevel interactions, from environmental conditions to cellular metabolism, is crucial for shaping effective prevention efforts, early diagnostic strategies, and evidence-based policies capable of mitigating the global rise of heat-associated kidney disease.

S. Yamada, Marcella Cipelli, P. F. Chagas et al. · Kidney360 · 0 citations