The multifaceted role of SOCS3 in colorectal cancer: molecular mechanisms and clinical implications
Clinically, reduced SOCS3 expression has been associated with lymph node metastasis, advanced TNM stage, and poorer prognosis, whereas higher SOCS3 levels may correlate with improved outcomes and chemosensitivity, and further translational studies are needed to validate SOCS3 as a biomarker and therapeutic target in CR...