Author

Roy Elias

3 papers indexed here

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Open access Oct 2026

Epithelial to mesenchymal transition and M2 macrophages drive aggressiveness in murine and human sarcomatoid urothelial carcinoma

Patients with majority variant subtype histology including sarcomatoid urothelial carcinoma (SUC) have poor outcomes and limited treatment options, and there are few preclinical resources to investigate rare histologic subtypes. We developed three novel variant subtype histology bladder cancer (BC) cell lines by findin...

Yujiro Hayashi, Roy Elias, Eugene F. Douglass et al. · bioRxiv · 0 citations

Open access Sep 2026

24 A Phase 1b/2 Study of Abemaciclib Plus Cabozantinib in Immune Checkpoint Blockade-Pretreated Metastatic Clear Cell Renal Cell Carcinoma and Translocation-Associated Renal Cell Carcinoma (NCT06835972)

Abstract Background There is a need for novel systemic therapies in patients with metastatic renal cell carcinoma (RCC) who progress on standard agents. A hallmark of clear cell RCC (ccRCC) is von Hippel Lindau (VHL) inactivation which affects downstream targets including vascular endothelial growth factor (VEGF). It a...

Sahil D. Doshi, Y. Ged, Andrea Knezevic et al. · The Oncologist · 0 citations

Review Jul 2026

Spatial distribution and prognostic significance of hemorrhagic imaging features in brain metastases from metastatic renal cell carcinoma

In this surgically managed RCC BM cohort, brain metastases from mRCC demonstrate nonrandom spatial distribution, with overrepresentation in posterior circulation and posterior cerebral artery territories.

Jia-Zhang Xing, Ardit Feinaj, Zsombor Ritter et al. · Journal of Neuro-Oncology · 0 citations