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Rong-Bing Hu

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Open access Sep 2026

Metastatic immune microenvironment remodeling by malignant epithelial cells drives colorectal cancer hepatic metastasis: Multi-omics insights

Highlights • First identified Scissor⁺ malignant cells driving CRC HM.• Constructed a Scissor-related prognostic signature for CRC patients with HM.• Elucidated mechanisms of Scissor⁺ malignant cells worsen the microenvironment of HM.• Firet confirmed Scissor⁺ malignant cells polarize macrophages into SELENOP⁺ TAMs.

Wen-Long Zhu, Ao Dong, Rong-Bing Hu et al. · 0 citations

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