R. Surges

Attention modulates hippocampal ripples in humans.

Hippocampal ripples are high-frequency events critical for memory consolidation, typically studied during sleep and quiet wakefulness. Emerging evidence suggests that ripples also occur during active behavior, yet their role in awake cognition remains unclear. Here, we demonstrate that changes in sustained attention mo...

Single-cell profiling reveals tumor grade-dependent immune remodeling in BRAFV600E-driven glioneuronal tumors

Automated hippocampal sclerosis detection, using AID-HS, shows robust performance across multi-centre paired 7T and 3T MRI

Background: Hippocampal sclerosis (HS) is a common cause of drug-resistant focal epilepsy (DRFE) and amenable to neurosurgical treatment. Detection relies on MRI but can be challenging. 7 Tesla (T) ultra-high field MRI and automated MRI post-processing tools have independently been shown to improve radiological diagnos...

Integrating the cognitive sequelae after temporal lobe surgery into daily life: a mixed methods approach to the consequences of average to severe memory decline

Whereas AMD was generally manageable and successfully integrat-ed into everyday life, SMD disrupted identity, autonomy, and expected life trajecto-ries, and current surgical pathways appear to address these cognitive sequelae insufficiently.