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Review Open access Sep 2026

Phenotypic and genetic relations between attention-deficit/hyperactivity disorder and substance use disorders

In this sample, ADHD was associated with increased risk for SUDs and earlier onset of substance use and genetic liability to ADHD was independently associated with multiple SUDs and SUD criteria counts.

Michael R. Setzer, R. Kember, Emily E. Hartwell et al. · 0 citations
Open access Jul 2026

Genome-Wide Association Studies and Deep-Learning Functional Annotation of Opioid Use Disorder across Three Ancestries in the All of Us Research Program

This study identifies DDX6 as a novel OUD risk locus, replicates associations with OPRM1 and FURIN, and highlights biologically plausible ancestry-specific signals in AFR and AMR populations.

Shaopeng Gu, D. Petrovitch, O. T. Hall et al. · 0 citations

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