Personalized single-cell transcriptomics reveals molecular diversity in Alzheimer’s disease
Alzheimer’s disease (AD) is highly heterogeneous and driven by diverse molecular and cellular mechanisms. Functional genomics investigates these mechanisms from genetic variants to gene expression and regulation. We performed personalized functional genomics analysis on population-scale single-nucleus RNA-seq data, wit...
P. Chandrashekar, S. Alatkar, Noah Cohen Kalafut et al.
· Nature Communications · 1 citation