Induced pluripotent stem cell reprogramming: methodological evolution and challenges in clinical translation
This review summarizes the trajectory of iPSC reprogramming technologies and identifies the core “translational triltrilas”, namely, the inherent tradeoffs between security, homogeneity, and scalability, and proposes a comprehensive strategy to overcome these bottlenecks.
Mengmeng Chen, Ning Zuo, Qi Wang et al.
· Frontiers in Cell and Develo... · 0 citations