Open access
Dec 2026
A novel oncolytic peptide synergizing with immunotherapy.
In a recent paper published in Nature, Yuan et al. described an acid-responsive membranolytic peptide that temporally separates lysosomes from later plasma membrane rupture, thereby converting oncolysis into immunogenic cell death. This elegant design permits systemic administration, elicits antigen-specific immunity,...
G. Kroemer, Xiao-Lian Deng, B. Sveinbjørnsson et al.
· Oncoimmunology · 0 citations