Nuha Husham Alhadethy

Drug-conditioned Residue Gating with Bidirectional Cross-attention for Drug-target Binding Affinity Prediction

Drug-target affinity (DTA) prediction remains challenging because drug and protein representations are frequently compressed before fine-grained atom-residue relationships and drug-specific residue relevance can be adequately modeled.In this study, a multimodal DTA framework is proposed in which molecular graphs are en...