RNA binding by ADARs prevents RNA interference from attacking self-produced dsRNA
The ability of an organism to distinguish between self and foreign double-stranded RNA (dsRNA) is central to eliciting an immune response when needed while preventing autoimmunity. Using Caenorhabditis elegans, we investigated the interplay between two host pathways that regulate dsRNA expression and function, adenosin...
Nabeel S. Ganem, Dean Light, Roni Haas et al.
· Science Advances · 0 citations