Chromatin-Assisted Targeting Enables Precise DNA Methylation Editing in Plants
SunTag-NOVA robustly installed DNA methylation and repressed transcription at the endogenous FWA, FT and TMM genes with minimal genome-wide off-target consequences, and establishes SunTag-NOVA as a specific epigenome-editing platform for plants.
Yan He, Ming Wang, T. J. Buckley et al.
· bioRxiv · 0 citations