Aug 2026
RUNX1-driven endothelial-to-mesenchymal transition contributes to remodelling in LMNA cardiomyopathy.
David Wu, D. Tripathi, Amit Manhas et al.
· European Heart Journal · 1 citation
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Generation of two homozygous iPSC lines carrying variants of uncertain significance in LMNA associated with cardiomyopathy
Two isogenic induced pluripotent stem cell lines carrying homozygous LMNA variants are generated by prime editing of a healthy donor iPSC line, providing a valuable platform for functional characterization and potential clinical reclassification of LMNA VUS.
Lu Liu, David Wu, Amit Manhas et al.
· Stem Cell Research · 0 citations