Mutational Landscape and Regulatory Network Analysis of TP53 and FOXA1 in Prostate Cancer
TP53 and FOXA1 mutations, observed in primary and metastatic castration-resistant prostate cancer, were associated with aggressive disease phenotypes and potential therapeutic resistance, and these findings highlight TP53 and FOXA1 as promising biomarkers and potential therapeutic targets in prostate cancer.
Shrijee Lakshkar, Pratha Tiwari, Heenal Bhatt et al.
· Medinformatics · 0 citations