Mechanism-aware and safety-validated AI for drug repurposing: a critical review and translational pharmacology framework
Background Artificial intelligence (AI)-assisted drug repurposing seeks to identify new therapeutic applications for existing drugs. Nevertheless, most of the existing studies are centered on prediction scores and candidate ranking, and there is still relatively little attention paid to the pharmacological mechanisms,...
Moumita Hazra, Harishchander Anandaram
· Frontiers in Pharmacology · 0 citations