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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Morgan Craig

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2 papers indexed here

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Open access Sep 2026

The trade-off between parsimony and model complexity for understanding biomedical mechanisms from mathematical models

The results highlight the limits of relying purely on statistical metrics for model selection, particularly when the goal is to obtain biological insight and underscore the importance of balancing model complexity to avoid overfitting and parameter unidentifiability.

Patricia Lamirande, M. Brunetti, Terry Easlick et al. · 0 citations
Open access Sep 2026

H3-K27M mutation alters the dynamics of human hematopoietic stem cells and delays erythroid differentiation

Acute myeloid leukemia (AML) is an aggressive blood cancer driven by genetic and epigenetic alterations that disrupt normal hematopoiesis. Among these, the histone H3-K27M mutation, originally identified in pediatric high-grade gliomas, reshapes gene repression programs by reducing global H3-K27 trimethylation. Althoug...

M. Brunetti, H. Dakik, Fatemeh Beigmohammadi et al. · 0 citations

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