Multi-omics characterization of 2 patients with biallelic HYOU1 variants reveals that HYOU1 deficiency impairs the unfolded protein response, disrupts early B cell development, and alters neutrophil granulation as well as IFN signalling, further establishing ER proteostasis as a contributor to human immune homeostasis.
Aida Idani, S. Bibi-Triki, Tristan Stemmelen et al.· Journal of human immunity· 0 citations
Moussavi-Harami et al. report that biallelic loss-of-function variants in PTPN6, encoding the immune-regulatory phosphatase SHP1, cause anemia and fatal lung hyperinflammation in families from diverse ethnic backgrounds.
S. Moussavi-Harami, M. Zinter, M. Motta et al.· Journal of Experimental Medi...· 0 citations
Findings indicate that B. cereus isolate 74 enhances maize salt tolerance through coordinated regulation of antioxidant defense systems and metabolic reprogramming, which provides novel insights into PGPR-mediated stress adaptation.
Maryam Zakavi, Hossein Askari, Mohammad Shahrooei· Microbiology Research· 0 citations
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