Phosphatidylethanolamine-mediated metabolic membrane remodeling in obesity-associated Alzheimer’s disease: mechanisms, neuroimmune crosstalk, and therapeutic potential
This review critically examines the molecular and cellular mechanisms underlying PE-mediated adipose–brain crosstalk in obesity-associated Alzheimer’s disease, with emphasis on mitochondrial dysfunction, blood–brain barrier disruption, ferroptosis, membrane remodeling, and microglial activation.